SYBX YTD ReturnSynlogic YTD Return




The SYBX YTD return is -36.52% with dividends reinvested through 07/10/2026. Investors often use YTD return to compare year-to-date performance across securities because current calendar year return information is important for tax planning.

This page shows SYBX YTD return, annualized return, start and end dates, and the growth of a hypothetical $10,000 investment with dividends reinvested.

Quick links: YTD Return Table  |  Performance Chart  |  Peers
Start date: 12/31/2025
End date: 07/10/2026
Start price/share: $1.12
End price/share: $0.71
Dividends collected/share: $0.00
SYBX YTD return: -36.52%
Annualized Gain: -70.15%
Starting investment: $10,000.00
Ending investment: $6,348.00
Years: 0.52


SYBX YTD return is presented with the assumption of reinvestments of any dividends on ex-date.
Compare SYBX YTD return (see YTD Return Meaning) versus benchmarks:

YTD Return S&P
YTD Return Dow
YTD Return Nasdaq 100
YTD Return Russell 2000
YTD Return Gold
YTD Return 10 Year Treasury
YTD Return By Sector
YTD Return on $10,000.00
Without Dividends Reinvested Into SYBX


Also see: SYBX Average Annual Return
Synlogic, Inc. is a biopharmaceutical company advancing novel therapeutics to transform the care of serious diseases. Co. is focused on rare metabolic disorders, with its lead program, labafenogene marselecobac (SYNB1934), studied in Synpheny-3, a global, pivotal Phase 3 study for patients with phenylketonuria (PKU), and SYNB1353, a potential treatment for homocystinuria (HCU). Co.'s early-stage pipeline includes product candidates for enteric hyperoxaluria, gout, and cystinuria, and has been fueled by a reproducible, proprietary approach that creates gastrointestinal (GI)-restricted, oral medicines with new enzymatic pathways designed to consume or produce specific biological targets. The SYBX YTD return is shown above.

The YTD Return on the SYBX YTD return page and across the coverage universe of our site, is a measure of the total return for a given investment year-to-date for the current calendar year (up to the end of prior trading session). Arguably, choosing the current calendar year for a measurement period is on the one hand completely arbitrary, but on the other hand a year-to-date look can be extremely useful in the context of our country's tax system which taxes gains and income on a calendar year basis.

Thus, researching Year-To-Date Returns is good practice for investors — whether SYBX YTD return or other benchmarks/peers — and when doing so it is also important to factor in dividends, because a financial instrument's YTD return is more than just the change in price if that instrument pays a dividend or coupon. Our website aims to empower investors by performing the SYBX YTD return calculation (with any dividends reinvested as applicable), and to provide a coverage universe of many stocks and ETFs to be able to compare YTD returns.
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Video: Don't Forget Dividends in YTD Return!
Synlogic (SYBX) is categorized under the Healthcare sector; to help you further research YTD return performance across stocks, below are some other companies in the same sector:

SYK YTD Return
SYNH YTD Return
SYRA YTD Return
SYRE YTD Return
SYRS YTD Return
TALK YTD Return
TALS YTD Return
TAOX YTD Return
TARA YTD Return
TARO YTD Return
More Healthcare companies »
 

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